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In conjunction with our policies, we work hand in hand with Diabetes Foundations in Nigeria, we also organise seminar on regularly basis to educate Diabetes Carriers, we enlightened, treat and managed diabetes cases for general well-being and healthy life with our Herbal Product.

We shall post the venue in due course, please check back or call 08023120010.. Read all»

 

  • Insulin

    Image 01

     

    DIAGRAM

    Computer-generated image of six insulin molecules assembled in a hexamer, highlighting the threefold symmetry, the zinc ions holding it together, and the histidine residues involved in zinc binding. Insulin is stored in the body as a hexamer, while the active form is the monomer. [1]

     

    Insulin is a peptide hormone, produced by beta cells of the pancreas, and is central to regulating carbohydrate and fat metabolism in the body. Insulin causes cells in the liver, skeletal muscles, and fat tissue to absorb glucose from the blood. In the liver and skeletal muscles, glucose is stored as glycogen, and in fat cells (adipocytes) it is stored as triglycerides.

    Image 02

    Insulin stops the use of fat as an energy source by inhibiting the release of glucagon. With the exception of the metabolic disorder diabetes mellitus and metabolic syndrome, insulin is provided within the body in a constant proportion to remove excess glucose from the blood, which otherwise would be toxic. When blood glucose levels fall below a certain level, the body begins to use stored sugar as an energy source through glycogenolysis, which breaks down the glycogen stored in the liver and muscles into glucose, which can then be utilized as an energy source. As a central metabolic control mechanism, its status is also used as a control signal to other body systems (such as amino acid uptake by body cells). In addition, it has several other anabolic effects throughout the body.

    When control of insulin levels fails, diabetes mellitus can result. As a consequence, insulin is used medically to treat some forms of diabetes mellitus. Patients with type 1 diabetes depend on external insulin (most commonly injected subcutaneously) for their survival because the hormone is no longer produced internallyImage 02.[2] Patients with type 2 diabetes are often insulin resistant and, because of such resistance, may suffer from a "relative" insulin deficiency. Some patients with type 2 diabetes may eventually require insulin if other medications fail to control blood glucose levels adequately. Over 40% of those with Type 2 diabetes require insulin as part of their diabetes management plan.

    The human insulin protein is composed of 51 amino acids, and has a molecular weight of 5808 Da. It is a dimer of an A-chain and a B-chain, which are linked together by disulfide bonds.

    Function of Udo2 Herbal Remedy Capsules or Udo2 Herbal Tea in the body: It function in form of insulin like, formulate the pancreatic operation repair the damaged insulin producing organs, and release insulin as well. The phytochemical research done on the plant, roots, and seeds we use was administered by researcher. The alcoholic and aqueous extract of our ingredients was studied for antidiabetic activity in alloxan induced diabetic rats by oral administration of extract 100mg/kg body weight for 15 days. The effect was compared with oral dose of 4.5mg/kg Glibenclamide. The alcoholic and aqueous extract of our tea leaves significantly decrease the blood glucose of hyperglycemic rats. Phytochemical study showed the presence of carbohydrates, carotene, fat, protein, phytin, amino acids, alanine, arginine, cystine, glutamic acid, glycine, hydroxyproline, leucine, serine, trypotophan, pipe colic acid, flavonoids and saponins. It is concluded that the leaf extract has significant antidiabetic activity, which lowered the fasting blood glucose level in alloxan induced diabetic rats.
    Keywords: Antidiabetic activity, alloxan, Glibenclamide.

    The history of herbal medicine is as old as human civilization, thousands of plant species growing throughout the world have medicinal uses containing active constituents that have direct action in the body. They are used both in herbal and conventional medicine.